Search results for "antioxidant properties"

showing 10 items of 12 documents

Direct chemical grafted curcumin on halloysite nanotubes as dual-responsive prodrug for pharmacological applications

2016

Covalently functionalized halloysite nanotubes (HNTs) were successfully employed as dual-responsive nanocarriers for curcumin (Cur). Particularly, we synthesized HNT-Cur prodrug with a controlled curcumin release on dependence of both intracellular glutathione (GSH) and pH conditions. In order to obtain HNT-Cur produgs, halloysite was firstly functionalized with cysteamine through disulphide linkage. Afterwards, curcumin molecules were chemically conjugated to the amino end groups of halloysite via Schiff's base formation. The successful functionalization of halloysite was proved by thermogravimetric analysis, FT-IR spectroscopy, dynamic light scattering and scanning electron microscopy. Ex…

Halloysite nanotubeAntiproliferative activity02 engineering and technology01 natural scienceshalloysite nanotubes covalent functionalization curcumin prodrugchemistry.chemical_compoundColloid and Surface ChemistryOrganic chemistryProdrugsProdrugSettore CHIM/02 - Chimica FisicaDrug CarriersNanotubesChemistryAntioxidant propertieFree Radical ScavengersSurfaces and InterfacesGeneral MedicineProdrug021001 nanoscience & nanotechnologyDrug deliveryAluminum Silicates0210 nano-technologyDrug carrierOxidation-ReductionBiotechnologyCurcuminCell SurvivalAntineoplastic AgentsHalloysite nanotubes Curcumin Prodrug Antiproliferative activity Antioxidant propertiesengineering.materialConjugated system010402 general chemistryHalloysiteCell Line TumorHumansPhysical and Theoretical ChemistryCell ProliferationSettore CHIM/06 - Chimica OrganicaCombinatorial chemistry0104 chemical sciencesKineticsMicroscopy Electron ScanningengineeringCurcuminSettore BIO/14 - FarmacologiaClayPharmaceuticsNanocarriers
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Morphological, chemical, and genetic diversity of wild myrtle(Myrtus communis L.) populations in Sicily

2016

Myrtus communis L. İs a shrub widespread in the Mediterranean area. The interest in this species is growing, mainly due to its pharmacological and aromatic properties. The overexploitation of wild populations induced increasing degradation of plant cover with serious risk of loss of genetic diversity. This research explored the morphological, chemical, and genetic diversity of wild myrtle populations in Sicily, with the aim to provide a first characterization of a core collection of 36 accessions from 7 localities for future domestication programs. Amplified fragment length polymorphism fingerprinting generated 152 polymorphic fragments. STRUCTURE analysis identified three genetic clusters …

0106 biological sciences0301 basic medicineDPPHMyrtleBiology01 natural sciencesAnalysis of molecular varianceFixation index03 medical and health scienceschemistry.chemical_compoundleaf antioxidant propertieSettore AGR/07 - Genetica AgrariaBotanyDomesticationGenetic resourcesGenetic diversityABTSMyrtus communisEcologyLeaf antioxidant propertiesMolecular markersForestryAgronomySettore AGR/02 - Agronomia E Coltivazioni Erbacee030104 developmental biologyAmplified fragment length polymorphismgenetic resourcesleaf antioxidant propertiesmyrtlemolecular markersAmplified fragment length polymorphismchemistryAmplified fragment length polymorphismgenetic resourceAgronomi010606 plant biology & botanyFood ScienceTURKISH JOURNAL OF AGRICULTURE AND FORESTRY
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Molecular Strategies for Targeting Antioxidants to Mitochondria: Therapeutic Implications

2015

Mitochondrial function and specifically its implication in cellular redox/oxidative balance is fundamental in controlling the life and death of cells, and has been implicated in a wide range of human pathologies. In this context, mitochondrial therapeutics, particularly those involving mitochondria-targeted antioxidants, have attracted increasing interest as potentially effective therapies for several human diseases. For the past 10 years, great progress has been made in the development and functional testing of molecules that specifically target mitochondria, and there has been special focus on compounds with antioxidant properties. In this review, we will discuss several such strategies, …

AntioxidantPhysiologyPlant AlkaloidsCellsAntioxidant propertiesmedicine.medical_treatmentClinical BiochemistryApoptosisContext (language use)Oxidative phosphorylationBiologyMitochondrionBiochemistryCellular redox/oxidative balanceAntioxidantsComprehensive Invited ReviewAutophagymedicineAnimalsHumansRedox activeMolecular BiologyGeneral Environmental ScienceHuman pathologiesAutophagyRedox active moleculesCell BiologyMitochondriaCell biologyBiochemistryGeneral Earth and Planetary SciencesMitochondrial functionTesting of moleculesOxidation-ReductionFunction (biology)Antioxidants & Redox Signaling
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Characterization of softwood and hardwood lignoboost kraft lignins with emphasis on their antioxidant activity

2014

Fractionation of softwood and hardwood LignoBoost kraft lignins, using sequential extraction with organic solvents of increasing hydrogen-bonding ability (dichloromethane, n-propanol, and methanol), was carried out. Using SEC, analytical pyrolysis, FTIR and UV/VIS spectroscopy, and chemical analytical methods, four fractions were obtained and characterized in terms of their yield, composition, functionality, lignin structural features, and antioxidant properties. In tests with free radicals (ABTS●+, DPPH●, O2●-) and the ORAC (oxygen radical absorbance capacity) assay, the high radical scavenging capacity of the lignin’s soluble fractions was demonstrated. The antioxidant activity of the fra…

ORAC assayEnvironmental EngineeringSoftwoodABTSOxygen radical absorbance capacityLignoBoost kraft ligninDPPHAntioxidant propertieslcsh:Biotechnologytechnology industry and agricultureBioengineeringmacromolecular substancesFractionationDPPH●chemistry.chemical_compoundchemistryABTS●+lcsh:TP248.13-248.65HardwoodOrganic chemistryLigninSolvent fractionationWaste Management and DisposalKraft paperO2●- assays
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Halloysite nanotubes loaded with peppermint essential oil as filler for functional biopolymer film

2016

Abstract The purpose of this paper is to show how a functional bionanocomposite film with both antioxidant and antimicrobial activities was successfully prepared by the filling of a pectin matrix with modified Halloysite nanotubes (HNT) containing the essential peppermint oil (PO). Firstly, HNT surfaces were functionalized with cucurbit[6]uril (CB[6]) molecules with the aim to enhance the affinity of the nanofiller towards PO, which was estimated by means of HPLC experiments. The HNT/CB[6] hybrid was characterized by several methods (thermogravimetry, FT-IR spectroscopy and scanning electron microscopy) highlighting the influence of the supramolecular interactions on the composition, therma…

Bridged-Ring CompoundsStaphylococcus aureusHalloysite nanotubes; Nanocomposite food packaging; Essential oil; Pectin; Antimicrobial and antioxidant propertiesfood.ingredientPolymers and PlasticsPectinHalloysite nanotube02 engineering and technologyengineering.material010402 general chemistry01 natural sciencesHalloysiteEssential oilNanocompositesContact anglefoodNanocomposite food packagingMaterials ChemistryEscherichia coliOrganic chemistryPlant OilsAntimicrobial and antioxidant propertiesAntimicrobial and antioxidant propertieSettore CHIM/02 - Chimica FisicaNanocompositeNanotubesChemistryOrganic ChemistryImidazolesMembranes ArtificialMentha piperitaSettore CHIM/06 - Chimica Organica021001 nanoscience & nanotechnologyPectin0104 chemical sciencesAnti-Bacterial AgentsThermogravimetrySolventChemical engineeringBiofilmsengineeringClayPectinsAluminum SilicatesBiopolymerBiocomposite0210 nano-technology
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Phytosterols: Nutritional Health Players in the Management of Obesity and Its Related Disorders

2020

Obesity and its related disorders, such as diabetes and cardiovascular risk, represent an emerging global health issue. Even though genetic factors seem to be the primary actors in the development and progression of these diseases, dietary choices also appear to be of crucial importance. A healthy diet combined with physical activity have been shown to ameliorate glycaemic levels and insulin sensitivity, reduce body weight and the risk of chronic diseases, and contribute to an overall improvement in quality of life. Among nutrients, phytosterols have become the focus of growing attention as novel functional foods in the management of metabolic disorders. Phytosterols are natural plant compo…

0301 basic medicineobesityPhysiologyClinical Biochemistryphytosterols030209 endocrinology & metabolismReviewBioinformaticsBiochemistryManagement of obesity03 medical and health scienceschemistry.chemical_compound0302 clinical medicineQuality of life (healthcare)Immune systemDiabetes mellitusGlobal healthmicrobiotaMedicinemetabolic disordersMolecular Biologybioactive compoundsbusiness.industryCholesterollcsh:RM1-950Insulin sensitivityCell Biologymedicine.diseaseObesityantioxidant properties030104 developmental biologylcsh:Therapeutics. Pharmacologychemistryanti-inflammatory propertiesbusinessAntioxidants
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Properties of New Strawberry Lines Compared with Well-Known Cultivars in Winter Planting System Conditions

2017

In Southern Italy and Sicily, strawberry cultivation is dominated by international cultivars such as ‘Candonga Sabrosa’, ‘Florida Fortuna’, ‘Sabrina’ and ‘Sant Andreas’. The primary objective of our study was to compare the field performance of two experimental lines and four established cultivars in a Sicilian representative strawberry production area. The second objective was to compare the fruits physic-chemical nutraceutical characteristics of these genotypes in response to different postharvest fruit storage temperatures. A supporting genetic analysis, via SSR markers, was also performed in order to establish genotype correlations. Our study confirmed the high result of ‘Florida Fortun…

0106 biological sciencesMediterranean climateStorage conditionsStrawberry fruit colourAntioxidant propertiesSettore AGR/04 - ORTICOLTURA E FLORICOLTURAPlant ScienceSettore AGR/04 - Orticoltura E Floricoltura010501 environmental sciencesBiologyHorticulture01 natural sciencesYield (wine)Antioxidant properties; Early production; Fragaria × ananassa Duch; Storage conditions; Strawberry fruit colour; Agronomy and Crop Science; Plant Science; HorticultureFragaria à ananassa DuchCultivarQuality characteristics0105 earth and related environmental sciencesEarly productionProduction areaSowingantioxidant properties early production Fragaria × ananassa Duch. strawberry fruit colour storage conditionsChemical qualityAgronomyPostharvestAgronomy and Crop Science010606 plant biology & botany
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Antioxidant properties of water-soluble gum from flaxseed hulls

2016

International audience; Soluble flaxseed gum (SFG) was extracted from flax (Linum usitatissimum) hulls using hot water, and its functional groups and antioxidant properties were investigated using infrared spectroscopy and different antioxidant assays (2,2-diphenyl-1-picrylhydrazyl (DPPH), 2,2'-azino-bis(3-ethylbenzothiazoline-6-sulphonic acid (ABTS), reducing power capacity, and β-carotene bleaching inhibition assay), respectively. The antioxidant capacity of SFG showed interesting DPPH radical-scavenging capacity (IC50 SFG = 2.5 mg·mL(-1)), strong ABTS radical scavenging activity (% inhibition ABTS = 75.6% ± 2.6% at 40 mg·mL(-1)), high reducing power capacity (RPSFG = 5 mg·mL(-1)), and po…

Linum[SDV.BIO]Life Sciences [q-bio]/BiotechnologyProperties of waterAntioxidantPhysiologyDPPH[SDV]Life Sciences [q-bio]medicine.medical_treatmentClinical BiochemistryInfrared spectroscopy02 engineering and technologyflax hullBiochemistryArticlechemistry.chemical_compoundAigua Anàlisi0404 agricultural biotechnologymedicineOrganic chemistry[SPI.GPROC]Engineering Sciences [physics]/Chemical and Process EngineeringFood scienceMolecular BiologyABTSbiologyPower capacity04 agricultural and veterinary sciencesCell Biology021001 nanoscience & nanotechnologybiology.organism_classification040401 food scienceantioxidant propertiesAntioxidant capacityflaxseed gumchemistryflax hull; flaxseed gum; antioxidant properties0210 nano-technology[SDV.AEN]Life Sciences [q-bio]/Food and Nutrition
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Essential oil of Citrus lumia Risso: Phytochemical profile, antioxidant properties and activity on the central nervous system

2018

Citrus lumia Risso Essential oil Antioxidant properties Anti-cholinesterase activity Cytotoxicity Neuroactive effects 1. Introduction Plants that produce essential oils (EOs) represent a large part of natural flora and an important resource in various fields such as pharmaceutical, food and cosmetic industries, due to their flavor, fra- grance and biological activity (Swamy et al., 2016). EOs play a pivotal role in the growth and colonization of plants, giving color and scent to reproductive organs, attracting pollinators, favoring seed dispersion (Sharifi-Rad et al., 2017), and defending the plant against abiotic (light, temperature, etc.) and biotics (herbivores, harmful insects and pa- t…

Central Nervous System0106 biological sciences0301 basic medicineCitrusAntioxidantCytotoxicitymedicine.medical_treatmentToxicology01 natural sciencesAntioxidantsEssential oillaw.inventionTerpeneMicechemistry.chemical_compoundLinaloollawSettore BIO/15 - Biologia FarmaceuticaFood scienceCitrus lumia Risso Essential oil Antioxidant properties Anti-cholinesterase activity Cytotoxicity Neuroactive effectsbiologyGeneral MedicineNeuroprotective AgentsPhytochemicalNeuroactive effectsAnti-cholinesterase activityAcyclic MonoterpenesAntioxidant propertiesNeuroprotectionGas Chromatography-Mass SpectrometryCell Line03 medical and health sciencesCyclohexenesOils VolatilemedicineAnimalsRats WistarIC50Essential oilCholinesteraseCell-Free SystemTerpenesAnti-cholinesterase activity; Antioxidant properties; Citrus lumia Risso; Cytotoxicity; Essential oil; Neuroactive effects; Food Science; Toxicology030104 developmental biologychemistryMicroscopy Electron ScanningMonoterpenesbiology.proteinCitrus lumia RissoCholinesterase InhibitorsLimonene010606 plant biology & botanyFood ScienceFood and Chemical Toxicology
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Profile of Fatty Acids, Tocopherols, Phytosterols and Polyphenols in Mediterranean Oils (Argan Oils, Olive Oils, Milk Thistle Seed Oils and Nigella S…

2019

Background: The effects of vegetable oils on human health depend on their components. Therefore, their profiles of lipid nutrients and polyphenols were determined. Objective: To establish and compare the fatty acid, tocopherol, phytosterol and polyphenol profiles of Mediterranean oils: cosmetic and dietary argan oils (AO; Morocco: Agadir, Berkane); olive oils (OO; Morocco, Spain, Tunisia); milk thistle seed oils (MTSO; Tunisia: Bizerte, Sousse, Zaghouane); nigella seed oil (NSO). Methods: The biochemical profiles were determined by gas chromatography-flame ionization, high performance liquid chromatography and gas chromatography, coupled with mass spectrometry as required. The antioxidant …

0301 basic medicineAntioxidantmedicine.medical_treatmentLinoleic acidmediterranean oilsTocopherolsAntioxidantsCell LineMice03 medical and health scienceschemistry.chemical_compound0302 clinical medicineDrug DiscoverymedicineAnimalsHumansMilk ThistlePlant OilsFood sciencecytoprotective activitiesOlive OilNigella2. Zero hungerPharmacologybiologyPhytosterolFatty AcidsPhytosterolsPolyphenolsfood and beverages[SDV.SP]Life Sciences [q-bio]/Pharmaceutical sciencesbiology.organism_classificationNigellaantioxidant propertiesOleic acid030104 developmental biologySpinasterolchemistryPolyphenol030220 oncology & carcinogenesisSeedsHydroxytyrosol[SDV.AEN]Life Sciences [q-bio]/Food and NutritionCurrent Pharmaceutical Design
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